Ascorbic Acid during Trypanosome Infection
نویسنده
چکیده
* The work presented in this paper was supported by a grant from the U. S. Public Health Service. In partial fulfillment of the requirements for the degree of Master of Science, Department of Pharmacology, University of Chicago. 1 VonBrand, T., Quart. Rev. Biol., 1938, 13, 41. metabolism of the host is affected during infection. Scheff and Csillag showed that the ascorbic acid content of the liver and blood of guinea pigs is lowered during infection with Trypanosoma brucei. Ascorbic acid administration was reported by Perla to increase the resistance of guinea pigs to infection with T. brucei, but not to alter the course of the infection in mice. These findings sup-
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